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The Art of Hormesis

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I've on occasion been asked, how do you remain fit? Now, I'm going to reveal my secret- Hormesis. What doesn't kill you makes you stronger. This is the basic layman concept of hormesis.  Our body responds to transient, acute physiologic stress or discomfort by triggering the adaptive stress response pathways. This reaction makes  our cells - especially the mitochondria, (the powerhouse of the cell) work better, making our body more efficient machines. The stress should be acute; chronic stress leads to debility and disease. One of the most common hormetic activity is exercise.  We stress our heart and muscle  to a certain degree and our body responds by making our muscles stronger, bigger and more adaptive to stamina. As in life and hormesis, too much of anything, including exercise is bad. I ran too much in my 40's and I injured myself then. So now in my 50's, running has become an occasional activity. Fasting is another hormetic activity. I have always skipped bre...